Ineffective cell delivery and poor intracellular accumulation are the main reasons why many drugs and therapeutic biomolecules cannot achieve good therapeutic effects. In order to solve this problem, scientists have studied a large number of biopolymers, such as collagen, gelatin, albumin, starch, cellulose and chitosan, etc., which can be used as delivery media for macromolecules and drug molecules.
At present, biopolymers have received more and more attention because of their biocompatibility, antibacterial properties, biodegradability and low immunogenicity, and they are widely used in drug delivery systems, tissue engineering, and wound healing dressings, etc. The development of biopolymers is of great significance for enhancing the cellular localization of biomolecules and improving their therapeutic effects. Therefore, a correct understanding of the polymer surface and bulk properties can provide new insights and ideas in biomedical and pharmaceutical applications.
Fig 1. Loading and delivery of biopolymers and drugs (Jacob, J.; et al. 2018)
Biopolymers are not only easy for surface modification but also interact with drug molecules in different ways. Creative Proteomics provides a technology platform dedicated to studying biopolymer-drug interactions, which can analyze the mechanical properties (such as size, shape, and elastic properties) and surface properties (such as chemical composition, surface charge, and adsorption energy) of particles. Our platform can also provide analysis of interactions including electrostatic interactions, hydrophobic interactions, covalent bonds of enzyme-sensitive groups for comprehensive study of their assembly behavior, drug loading performance, and drug release characteristics, making them ideal for drug delivery.
Customers can choose certain services according to project requirements, or contact us directly for consultation, and our expert team will provide you with a customized experimental program.
There are more and more researches on biopolymers. Creative Proteomics has recruited a group of experienced researchers and combined a variety of mature technologies to form our unique platform to ensure that we can provide customers with high accuracy and time-saving service. We are honored to be your competent research assistant.