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Introduction

As a trusted contract research organization, Creative Proteomics focuses on studying the interactions between various molecules, helping customers to understand biology, medicine, and materials science at a deeper level. At present, we have accumulated nearly 20 years of experience in this field, with experienced scientists and various world-class technology platforms. In addition to technical services, we can also provide customers with solutions to support you in the discovery and development of molecular interactions.

With our abundant laboratory capabilities, Creative Proteomics provides our customers with numerous advanced and powerful technology platforms to study the interactions between various substances, including proteins, nucleic acids, carbohydrates, graphene, lipids, and small molecules drugs, etc. In addition, we have recruited a large number of interdisciplinary scientists to manage our technology platform. Our reliable, efficient, and excellent technology platforms have won us countless praises internationally.

Platforms

Our Services

We provide many advanced and highly accurate technology platforms to help customers study molecular interactions, including but not limited to:

Biomolecule Interaction General Technology

Molecular Dynamics Simulations Surface Plasmon Resonance (SPR) Microscale Thermophoresis (MST) Biolayer Interferometry (BLI) Circular Dichroism (CD) Analytical Ultracentrifugation (AUC) Dynamic Light Scattering (DLS) Nuclear Magnetic Resonance (NMR) Spectroscopy X-ray Crystallography Microscopy Imaging Flow Cytometry Fluorescence Recovery after Photobleaching (FRAP) Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Sum Frequency Generation (SFG) Vibrational Spectroscopy Mass Spectrometry

Protein-Protein Interaction Analysis

Affinity Purification-Mass Spectrometry (AP-MS) Chemical Crosslinking-Mass Spectrometry (XL-MS) Mammalian Two-hybrid (M2H) Proximity-dependent Biotin Identification (BioID) BIoID2 miniTurbo TurboID Protein Crosslink Crosslinking Protein Interaction Analysis GST Pull-Down Immunoprecipitation Tandem Affinity Purification (TAP) TAP-MS HDX-MS Epitope Mapping Yeast/Bacterial Two-Hybrid Label Transfer Protein Interaction Analysis Bimolecular Fluorescence Complementation (BiFC) Isothermal Titration Calorimetry (ITC) Fluorescence Resonance Energy Transfer (FRET) Bioluminescence Resonance Energy Transfer (BRET) Mating-based Split-Ubiquitin System (mbSUS) Protein-Fragment Complementation Assay (PCA) Enzyme Fragment Complementation Assay (EFCA) Mammalian Protein-Protein Interaction Trap (MAPPIT) Reverse Mammalian Protein-Protein Interaction Trap (Reverse MAPPIT) SILAC-Immunoprecipitation Limited Proteolysis–Mass Spectrometry (LiP-MS) Far-Western Blot

Protein-DNA Interactions

DNase I Footprinting Electrophoretic Mobility Shift Assay (EMSA) DNA Pull Down Yeast/Bacterial Two-Hybrid Yeast One Hybrid DAP-Seq (DNA Affinity Purification Sequencing)
Immunoprecipitation

Protein-RNA Interactions

CLIP-Seq ChiRP-MS
RNA Antisense Purification (RAP)
RNA Immunoprecipitation (RIP) RNA Pull Down Yeast Three-hybrid (Y3H) Electrophoretic Mobility Shift Assay (EMSA) RNA Circular Dichroism MS2-BioTRAP Dual Luciferase Reporter Gene Assay

Protein-Lipid lnteractions

Protein-Small Molecule lnteraction Analysis

Protein-Small Molecule lnteraction Analysis

Drug Affinity Responsive Target Stability (DARTS) Analysis Molecular Docking Molecular Dynamics Simulations Limited Proteolysis–Mass Spectrometry (LiP-MS)

Other Protein Interactions Platform

Pull-Down Hydrogen Deuterium Exchange (HDX) Mass Spectrometry Differential Scanning Fluorimetry (DSF) Protein Microarray Glycan Microarrays Phage Display

Nucleic Acid Interaction

ChiRP-Seq RAP-Seq RIC-seq

Customers can choose a certain technology according to the needs of the project, or contact us directly for consultation, and our expert team will provide you with a customized experimental program.

Why Choose Us?

Precision and Accuracy: Our platform offers unparalleled precision and accuracy in studying molecular interactions, ensuring reliable and reproducible results.

Versatility: With a diverse range of techniques and methodologies, our platform is versatile and adaptable to various research needs across different biological systems.

Efficiency: Through high-throughput screening and advanced analytical techniques, we enable efficient data collection and analysis, saving both time and resources.

Insightful Analysis: Our platform provides insightful analysis of molecular interactions, empowering researchers with valuable insights into biological processes and pathways.

Collaborative Opportunities: We welcome collaboration and partnership opportunities to further advance research in molecular interaction analysis and drive scientific discovery.

Creative Proteomics is an international company with rich experience and numerous successful cases in molecular interaction analysis. The services we provide are subject to strict quality control, and our advanced technology platform will be upgraded in time. We are honored to be your competent research assistant.

* This service is for RESEARCH USE ONLY, not intended for any clinical use.