Nuclear Magnetic Resonance (NMR) Spectroscopy

Nuclear Magnetic Resonance (NMR) Spectroscopy

Introduction

Nuclear magnetic resonance (NMR) spectroscopy is an indispensable analytical technique in biology and medicine. Based on the quantum mechanical properties of spin, it is very sensitive to the local magnetic/chemical environment with atomic resolution. The NMR interaction energy is very small, they rely on radio frequency (RF) as probe radiation. Because of its non-destructive and non-invasive, NMR becomes an ideal tool for studying the composition of substances and the interaction of biomolecules.

Creative Proteomics' professional NMR equipment platform includes multiple automated NMR spectrometers, which can provide various measurement services for students and scientists all over the world, and provide knowledge and support in all aspects of NMR research, including isotope labeling, data analysis and structure calculations, etc. In addition, we also provide advice on all issues related to NMR spectroscopy.

NMR in drug design and discoveryFigure 1. NMR in drug design and discovery

Services

Customers can use the 400 MHz spectrometers we provide to perform routine NMR experiments. If more precise measurement is required, we provide several devices with higher field strength, such as 600 MHz, 700 MHz, and 900 MHz NMR spectrometers. Please see the table below for specific information.

Brief information of NMR equipment provided by Creative Proteomics - Creative ProteomicsTable 1. Brief information of NMR equipment provided by Creative Proteomics - Creative Proteomics

Creative Proteomics has a large number of professional NMR technical experts. With professional skills and rich experience, we provide customers with efficient and accurate NMR related services, including but not limited to the following aspects.

  • Chemical structure identification (solid and liquid)
  • Chemical composition identification (solid and liquid)
  • Identify and quantify impurity (solid and liquid)
  • Qualitative and quantitative NMR method development
  • Conformation and structure analysis (solid and liquid)
  • Chemical exchange analysis (solid and liquid)
  • Molecular mobility rate analysis (solid and liquid)

Customers can choose different technologies and equipment according to project requirements, or contact us directly for consultation, and our expert team will provide you with customized experimental procedures.

Applications

  • Research on the interaction mechanism of various substances
  • Pharmaceutical development
  • Food composition analysis and safety identification
  • Lithium-ion battery research

Creative Proteomics is an international biotechnology company, focusing on the research of intermolecular interactions and other related fields. In order to provide customers with higher quality and efficient services, we have established many powerful technology platforms to support our services. Customers can complete a large number of advanced and cutting-edge experiments and projects on our platforms.

Reference

  1. Emwas, A.H.; et al. NMR as a "gold standard" method in drug design and discovery. Molecules. 2020, 25(20). 
* This service is for RESEARCH USE ONLY, not intended for any clinical use.

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