Virus-Virus Interaction Analysis

Background

The interaction between virus and host has aroused widespread concern in virology research. But when more than one virus infects the host, virus-virus interaction may occur, which is caused by simultaneous or sequential infection of different types of virus strains. Coinfection and subsequent social interactions can change the pathogenicity and genetic composition of the virus, or some characteristics of the host. In addition, these interactions may also change due to the ecological environment and molecular mechanisms within and between the host. At present, scientists have proposed a classification system that can divide the virus-virus interactions into three major categories: (1) direct interactions between viral genes or gene products; (2) Indirect interactions caused by changes in the host environment; (3) immunological interactions.

Although many such interactions have been discovered, they are rarely studied systematically. More and more evidence show that the virus-virus interaction is a universal phenomenon, and the study of this phenomenon is essential for understanding the pathogenic mechanism of viruses. Although there is still a lack of extensive theoretical research on virus-virus interactions, the research in recent years has made theoretical breakthroughs to answer some key social virological questions, so the integration of these studies will greatly help us study virology.

Different types of virusesFig 1. Different types of viruses

Services

The systematic study of virus-virus interaction is a complex and challenging task, but by using the right tools, theoretical methods and research systems, significant progress will be made in understanding the social life of viruses.

The virus-virus interaction research platform established by Creative Proteomics has a large number of outstanding virology experts, who are good at studying viruses through high-throughput single-cell and subcellular technologies. In addition to sequencing, single-cell microfluidics, etc., we are also vigorously developing new experimental techniques created by using existing tools. After using high-throughput technology, we will provide hypothesis testing or model verification to perfect the experiment. In addition, we have also recruited a large number of talents in biology, chemistry, and bioinformatics. Our platform encourages experts in various fields to gather together to study the principle of virus-virus interaction and convey its importance to a wider range of biology, microorganisms, and medicine.

Customers can choose a certain technology according to the needs of the project, or contact us directly for consultation, and our expert team will provide you with a customized experimental program.

Applications

  • Virus-virus interaction research
  • Pathogenic mechanism research
  • Virus life cycle research
  • New method development in virology
  • Antiviral drug development

Highlights

  • High throughput
  • Provides multiple verification methods
  • Fast and high sensitivity
  • Multi-disciplinary combination
  • Tailored experimental program  

Creative Proteomics has provided high-quality virus-related services to scientists from all over the world. The virus-virus interaction technology platform we have established can help customers explore the social virological events and pathogenic mechanisms in a comprehensive and multidisciplinary manner, and ultimately promote the development of new antiviral drugs. We are honored to be your competent research assistant.

References

  1. DaPalma, T.; et al. A systematic approach to virus-virus interactions. Virus Research. 2010, 149(1): 1-9.
  2. Díaz-Muñoz, S.L. Uncovering virus-virus interactions by unifying approaches and harnessing high-throughput tools. mSystems. 2019, 4(3).
* This service is for RESEARCH USE ONLY, not intended for any clinical use.