Drug-Related Interactions

Drug-Related Interactions

Background

Other Molecular Interactions

In addition to common biological macromolecules such as proteins, nucleic acids, and carbohydrates, there are also many interactions between other substances, which are important for biology and medicine.

When the patient takes two or more drugs at the same time or within a certain period of time, it is very likely that a compound effect will be produced, which can enhance the drug effect, reduce the side effects, or reduce the drug effect and appear new side effects. Therefore, the study of drug-drug interactions can greatly promote safe and effective combination drugs, which is extremely important to improve the quality of medical treatment.

At present, many people use medicinal natural products, the natural product-drug interaction (NPDI) is a common hidden problem in clinical practice. These interactions are based on the same pharmacokinetic and pharmacodynamic principles as drug-drug interactions. Clinically, NPDI is likely to change the efficacy and safety of traditional drugs, so a systematic study of their interaction is imminent.

Due to poor solubility, low bioavailability, and short circulation time in vivo, some drugs are quickly cleared in the body and have poor therapeutic effects. To solve this problem, scientists have developed a series of biopolymers as drug delivery carriers. Therefore, in order to further develop and optimize biopolymers and make them better used in biomedicine, it is necessary to fully study the interaction between biopolymers and drugs.

Our Services

Highlights

  • Combination of experimental and calculation methods
  • High resolution and high accuracy
  • Experienced and well-trained technicians
  • Powerful data analysis tools
  • Multidisciplinary integration
  • Cost-effective¬†

Creative Proteomics is a biotechnology company that studies intermolecular interactions in all aspects, we have provided help to tens of thousands of scientists all over the world. In addition to common biological macromolecules, we have also established various technology platforms to complete the interaction research between other molecules such as drugs, biopolymers, natural products, etc., to promote the development of biology and medicine. We are honored to be your competent research assistant. 

References

  1. Palleria C.; et al. Pharmacokinetic drug-drug interaction and their implication in clinical management. J Res Med Sci. 2013, 18(7): 601-610.
  2. Amponsah-Efah, K.K.; et al. Characterizing drug-polymer interactions in aqueous solution with analytical ultracentrifugation. Mol. Pharmaceutics. 2021, 18(1): 246-256.
* This service is for RESEARCH USE ONLY, not intended for any clinical use.