Mass Spectrometry

Mass Spectrometry

Introduction

Mass Spectrometry Platform

Mass spectrometry is a powerful analysis tool in proteomics and metabolomics, which can be used to measure the mass-to-charge ratio (m/z) of one or more molecules present in a sample. Generally, mass spectrometers can be used to identify unknown compounds, quantify known compounds, and determine molecular structure and chemical properties by measuring molecular weight. The three basic components of a mass spectrometer include ionization source, mass analyzer, and ion detection system.

Creative Proteomics' mass spectrometry platform was established 20 years ago. During this period, it has been continuously upgraded to form a platform with a large number of advanced equipment and related software. The platform is managed by experts in the protein field and professional mass spectrometry engineers, and can provide our collaborators with efficient, accurate, and cost-effective services.

Proteomics experiment workflow schematicFigure 1. Proteomics experiment workflow schematic (Woods, A.G.; et al. 2019)

Services

Creative Proteomics aims to provide customers with the best mass spectrometry services. We can provide services from experimental design, sample preparation, quality control, MS processing, bioinformatics and statistical analysis, etc. In our platform, customers can perform almost all researches of interest, such as proteome analysis, high-resolution analysis of small molecules, and quantification of small molecules in complex environments, etc.

Our equipment includes but is not limited to:

  • Bruker MaXis Impact
  • Dionex Ultimate 3000 2D-LC
  • Ultimate nanoUPLC
  • Waters XEVO TQ-S
  • Thermo ScientificTM Q ExactiveTM HF-X Hybrid Quadrupole-OrbitrapTM MS
  • Thermo ScientificTM Orbitrap FusionTM TribridTM MS

We also provide a variety of different data processing software, including but not limited to:

  • Mascot Server 2.7
  • Metaboscape Bruker
  • Merox 2.0
  • PEAKS X Pro
  • Thermo ScientificTM Proteome DiscovererTM 2.4 software

Customers can choose different technology platforms according to project requirements, or contact us directly for consultation, and our expert team will provide you with customized experimental procedures.

Applications

  • Interactomics
  • Protein and peptide identification
  • Post-translational modification analysis
  • Comparison of proteomes
  • Quality measurement
  • Targeted proteomics research

Creative Proteomics is an international biotechnology company dedicated to research in molecular interactions and other related fields. We have established a mature mass spectrometry platform, which includes a large number of sophisticated instruments and professional technicians, which can help customers to more effectively study the interaction between proteins, peptides, small molecules, etc. Our one-stop service is designed to save customers time and money.

Reference

  1. Woods, A.G.; et al. Mass spectrometry for proteomics-based investigation. Advances in Experimental Medicine and Biology. 2019.
* This service is for RESEARCH USE ONLY, not intended for any clinical use.

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